This points out why 1 lorazepam dose, Even with its shorter serum 50 %-daily life, has additional prolonged peak outcomes than an equivalent diazepam dose.[99] Lorazepam is promptly conjugated at its 3-hydroxy team into lorazepam glucuronide that is then excreted while in the urine. Lorazepam glucuronide has no demonstrable CNS exercise in animals.
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